Blighted overload (4)

High alchemy turns Blighted overload (4) into 30 gp. Buying one at 36,573 gp (its guide price, as it has not traded today) and casting with a nature rune at 138 gp costs 36,711 gp. That is a loss of 36,681 gp per cast at its guide price, so it is not worth alching for profit right now.