Sigil of the Forager

High alchemy turns Sigil of the Forager into 12,000 gp. Buying one at 100,000 gp (its guide price, as it has not traded today) and casting with a nature rune at 137 gp costs 100,137 gp. That is a loss of 88,137 gp per cast at its guide price, so it is not worth alching for profit right now.