Trinket of advanced weaponry

High alchemy turns Trinket of advanced weaponry into 6,000 gp. Buying one at 155,550 gp (its guide price, as it has not traded today) and casting with a nature rune at 137 gp costs 155,687 gp. That is a loss of 149,687 gp per cast at its guide price, so it is not worth alching for profit right now.