Trinket of vengeance

High alchemy turns Trinket of vengeance into 6,000 gp. Buying one at 141,342 gp (its guide price, as it has not traded today) and casting with a nature rune at 138 gp costs 141,480 gp. That is a loss of 135,480 gp per cast at its guide price, so it is not worth alching for profit right now.